Friday, February 01, 2013

Depressing anti-depressant news, Zimbabwe is almost broke and LeBron is expensive


- Folks, there is depressing news from the world of anti-depressants. If a consumer class-action suit filed in the United States District Court for the Northern District of California, San Jose Division, before Magistrate Judge Paul Singh Grewal, is to be believed then depressed people may as well take a sugar pill rather than pay top dollar for Zoloft (Sertraline hydrochloride). Pfizer Inc., the drug’s manufacturer, is being sued by plaintiff Laura Plumlee, who claims she took Zoloft for three years with no discernable results. In the suit, she argues that the antidepressant medication offered no more benefit than a placebo. Her attorney, R. Brent Wisner (of course this ass hat has a first initial in front of his name in typical lawyer pomposity) argues that the Food and Drug Administration should not have approved Zoloft because Pfizer had not published some clinical trials which demonstrated that the medication was not significantly different to a placebo. The company is accused of deceptively marketing Zoloft as a "highly effective treatment for depression” while knowing full well that it had virtually no impact on the illness. The lawsuit hinges on several key points, most notably that most Zoloft clinical trials that focused on its efficacy proved to be either negative or neutral and in these studies, Zoloft was not significantly better than a placebo in relieving the symptoms of depression. In fact, the suit claims that placebos often deliverd better results than the actual drugs and that Pfizer was fully aware of this fact. Pfizer knew about how effective or ineffective Zoloft was, "as documented in internal company documents discussed in the complaint,” the suit says. Yet oddly enough, Pfizer kept right on making and manufacturing Zoloft as if everything were copasetic. As the lawsuit’s theory goes, convincing consumers and doctors that Zoloft was highly effective in treating depression ensured the company of continuing to take in huge profits. This supposedly sinister plot was carried out through a "a comprehensive scheme of selective publication of clinical trial data, ghostwriting positive manuscripts about the efficacy of Zoloft, paying prominent physicians (known as Key Opinion Leader or "KOLS") to tout the efficacy and safety of Zoloft, and misleading advertising on television and in magazines." Since the drug launched in 1991, sales have netted more than $30 billion for Pfizer and before its patent expired in 2007, Zoloft's annual sales exceeded $3 billion each year. Even today in a more competitive market, the drug still brings in $500 million annually……..


- It’s about time someone was punished for the music of the Spice Skanks. Since God-awful music is still not a legally acceptable reason to sue someone in Britain, this will have to do for now. Instead of Scary, Sporty, Posh or Skanky Spice being punished, a Nottingham, England resident has been evicted from his home after repeatedly playing the group's song “Viva Forever” at ear-splitting volume. Gavin Townroe used to live in Digby Court in the Lenton area of Nottingham and now he doesn’t. He was booted for repeatedly playing loud music, leading one of his neighbors to lodge a complaint last January. Following the complaint, Townroe was later given a citation because one neighbor called off work because he was so fatigued due to a lack of sleep. In spite of that development, Townroe continued to disrupt those around him and was subsequently given a six-week suspended jail term in October. When that wasn’t enough to silence this kook’s abiding love for one of the worst musical acts of all-time, the Nottingham City Council took action and successfully slapped Townroe with an eviction notice mandating he leave his home by February 4 and also pay costs of £913. "Despite being warned, Mr. Townroe had a total disregard for his neighbours. At times the volume was so loud residents would leave their properties to escape the music,” said police spokesman Wayne Cliff. Neighbors will undoubteldy be relieved to not hear a poorly sung challenge to “Spice up your life” at 8 a.m. or have to listen to the decree that, “If you wanna be my lover, you gotta get with my friends.”The story continues a well-deserved run of bad fortune for the Spice Skanks, as a West End musical written by Jennifer Saunders and using the group’s music was roundly panned by critics when it opened in London last fall………


- Way to address problems head on and in productive fashion, residents of Aspen, Colorado’s West End neighborhood. Those living in this upscale area are sick and tired of motorists doing what they do everywhere else on God’s great spinning Earth, speeding. Because they’re special and don’t want to put up with it, these whiny Coloradans recently pushed their city council to lower the speed limit. Initially, Mayor Mick Ireland suggested an 18 mph limit because the number is out of the ordinary, but council members decided to adopt the spirit of the X-Games, which their city hosts each winter, and either go big or go home. They went even lower and decided to drop the proposed limit down to 14 mph. That change led to one of the more unusual speed limit signs around, one that reads, “Speed Limit 14 mph.” To outfit the entire area with signs denoting the new law, a total of 60 signs will be ordred and at a cost of less than $500 per sign, the estimated cost for the change will be more than $27,000. That obviously means the city’s police department will simply need to write more tickets to offset the cost, which probably won't be a problem. But the lower speed limit has to be making an impact, right? “We are still receiving complaints about speeding,” City Engineer Trish Aragon said. “Although from an engineering perspective, we don’t see that they’re speeding. But the perception still is that vehicles are speeding through the neighborhood.” Thanks for that insightful observation, Trish. To all of the complainers who hoped the change would discourage motorists from cutting through the neighborhood to avoid congestion on Highway 82 near the S-curves….well….suck it…….


- As former women’s tennis eye candy Anna Kournikova once told a young male fan, “You can’t afford me.” Put reigning NBA Most Valuable Player and Miami Heat star LeBron James in the same category because clearly, LBJ doesn’t believe there is a paycheck in existence big enough to pay him what he’s worth. In fact, James doesn't think it's possible to be paid his actual value under the current NBA rules. "What I do on the floor shows my value. At the end of the day, I don't think my value on the floor can really be compensated for anyways because of the (collective bargaining agreement)," James said. "If you want the truth. If this was baseball, it'd be up, I mean way up there." Glad to know you’re so high on your own value, ‘Bron. Maybe you should have taken your talents to MLB and then you could have scored than contract worth $35 million annually. Instead, James is toiling away for a mere  $17.5 million this season, which is tied for 13-highest in the NBA. He’s well behind league earnings leader Kobe Bryant, who is making $27.8 million for the Los Angeles Lakers. Back in 2011, James was asked what it would take to get him to play in Europe during the NBA's lockout and suggested he could be worth $50 million a year. Some teams are looking to shed payroll before a new more stringent luxury tax arrives next season and have traded away some of their most expensive assets to do so. The Heat are in decent shape because James and teammates Dwyane Wade and Chris Bosh all took less than the maximum salary when they signed three years ago. Rather than let his “sacrifice” go unnoticed, James wanted to make sure everyone knows about his unselfishness – before immediately insisting that credit didn’t matter to him. "I have not had a full max deal yet in my career -- that's a story untold," James said. "I don't get (the credit) for it. That doesn't matter to me, playing the game is what matters to me. Financially, I'll sacrifice for the team. It shows for some of the top guys, it isn't all about money. That's the genuine side of this, it's about winning. I understand that." Yes, it’s about winning and being able to take less money because you also make $40 million per year in endorsements and sponsorships and work in a state with no individual income tax……..

- After a late night at the bar and with a splitting headache from one too many encounters with the bottom of a just-drained red solo cup, Zimbabwe stumbled to the ATM the next morning looking for a few bucks to get some quality hangover food and man, was Zimbabwe stunned to see how much money it had left in its checking account. Yes, this is Zimbabwe the country, the one in Africa, and unlike your bro-ham who needs a few bucks for a chalupa and a burrito to soak up the excess alcohol in his system but only has $2.27 left in his account, Zimbabwe is a nation of several million impoverished people and a government to run and it only has $217 left in the bank. Not $217 million or $217 billion, but $217. Finance Minister Tendai Biti confirmed the dire financial prognosis this week and admitted that paltry amount is all that’s left in the country's public accounts after it paid its civil servants last week. Biti pointed out that having been paid for what might be the last time for a while, those civil servants were probably better off than the state. To the obvious question of how the hell an entire nation gets to this point: After a decade of inflation hit 500 billion percent in 2008 — leading to the issuance of 100 trillion-dollar bills in Zimbabwean currency — the country switched to the U.S. dollar and despite the change, the debt the country built up during those years of nationalist rule by President Robert Mugabe drained its cash reserves and depleted its tax base. Its current coalition government was credited by the International Monetary Fund in September with taming inflation and stabilizing the economy, but the Mugabe-fueled aftershocks remain. Salary for civil servants accounts for 73 percent of the national budget but to hear Biti talk, those servants may not get their coffers replenished again any time soon. "The government finances are in a paralysis state at the present moment," he said…….

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